Androgens repress expression of the F-box protein Skp2 via p107 dependent and independent mechanisms in LNCaP prostate cancer cells

BACKGROUND: Androgens control homeostasis of the normal prostate and growth of prostate cancer (PCa) through the androgen receptor (AR) by regulating gene networks involving in cell proliferation, differentiation, and survival. We demonstrated previously that expression of Skp2, a key protein regula...

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Vydáno v:Prostate
Hlavní autoři: Jiang, Jingting, Pan, Yunqian, Regan, Kevin M., Wu, Changping, Zhang, Xueguang, Tindall, Donald J., Huang, Haojie
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413901/
https://ncbi.nlm.nih.gov/pubmed/21630295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21430
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