Mechanism of action and therapeutic efficacy of Aurora kinase B inhibition in MYC overexpressing medulloblastoma

Medulloblastoma comprises four molecular subgroups of which Group 3 medulloblastoma is characterized by MYC amplification and MYC overexpression. Lymphoma cells expressing high levels of MYC are susceptible to apoptosis following treatment with inhibitors of mitosis. One of the key regulatory kinase...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Diaz, Roberto Jose, Golbourn, Brian, Faria, Claudia, Picard, Daniel, Shih, David, Raynaud, Denis, Leadly, Michael, MacKenzie, Danielle, Bryant, Melissa, Bebenek, Matthew, Smith, Christian A., Taylor, Michael D., Huang, Annie, Rutka, James T.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413659/
https://ncbi.nlm.nih.gov/pubmed/25739120
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker