Thrombospondin-1 mimetics are promising novel therapeutics for MYC-associated medulloblastoma

BACKGROUND: Medulloblastoma (MB) comprises four subtypes of which group 3 MB are the most aggressive. Although overall survival for MB has improved, the outcome of group 3 MB remains dismal. C-MYC (MYC) amplification or MYC overexpression which characterizes group 3 MB is a strong negative prognosti...

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Detalhes bibliográficos
Publicado no:Neurooncol Adv
Main Authors: Chan, Tiffany S Y, Picard, Daniel, Hawkins, Cynthia E, Lu, Mei, Pfister, Stefan, Korshunov, Andrey, Roussel, Martine F, Wechsler-Reya, Robert J, Henkin, Jack, Bouffet, Eric, Huang, Annie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7890793/
https://ncbi.nlm.nih.gov/pubmed/33629064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab002
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