The mTOR Inhibitor Rapamycin Suppresses DNA Double-Strand Break Repair

mTOR (mammalian target of rapamycin) signaling plays a key role in the development of many tumor types. Therefore, mTOR is an attractive target for cancer therapeutics. Although mTOR inhibitors are thought to have radiosensitization activity, the molecular bases remain largely unknown. Here we show...

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Publicado no:Radiat Res
Main Authors: Chen, Honghong, Ma, Zhefu, Vanderwaal, Robert P., Feng, Zhihui, Gonzalez-Suarez, Ignacio, Wang, Shenming, Zhang, Jiuqin, Roti Roti, Joseph L., Gonzalo, Susana, Zhang, Junran
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412148/
https://ncbi.nlm.nih.gov/pubmed/21268715
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