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Cardiac Expression of Human Type 2 Iodothyronine Deiodinase Increases Glucose Metabolism and Protects Against Doxorubicin-induced Cardiac Dysfunction in Male Mice

Altered glucose metabolism in the heart is an important characteristic of cardiovascular and metabolic disease. Because thyroid hormones have major effects on peripheral metabolism, we examined the metabolic effects of heart-selective increase in T3 using transgenic mice expressing human type 2 iodo...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Hong, Eun-Gyoung, Kim, Brian W., Young Jung, Dae, Hun Kim, Jong, Yu, Tim, Seixas Da Silva, Wagner, Friedline, Randall H., Bianco, Suzy D., Seslar, Stephen P., Wakimoto, Hiroko, Berul, Charles I., Russell, Kerry S., Won Lee, Ki, Larsen, P. Reed, Bianco, Antonio C., Kim, Jason K.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411365/
https://ncbi.nlm.nih.gov/pubmed/23861374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-2261
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