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Targeting of metastasis-promoting tumor-associated fibroblasts and modulation of pancreatic tumor-associated stroma with a carboxymethylcellulose-docetaxel nanoparticle

Pancreatic ductal adenocarcinomas are characterized by the desmoplastic reaction, a dense fibrous stroma that has been shown to be supportive of tumor cell growth, invasion, and metastasis, and has been associated with resistance to chemotherapy and reduced patient survival. Here, we investigated ta...

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Foilsithe in:J Control Release
Main Authors: Ernsting, Mark J., Hoang, Bryan, Lohse, Ines, Undzys, Elijus, Cao, Pinjiang, Do, Trevor, Gill, Bethany, Pintilie, Melania, Hedley, David, Li, Shyh-Dar
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409566/
https://ncbi.nlm.nih.gov/pubmed/25804872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.03.023
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