Docetaxel-Carboxymethylcellulose Nanoparticles Target Cells via a SPARC and Albumin Dependent Mechanism

Cellax, a polymer-docetaxel (DTX) conjugate that self-assembled into 120 nm particles, displayed significant enhancements in safety and efficacy over native DTX across a number of primary and metastatic tumor models. Despite these exciting preclinical data, the underlying mechanism of delivery of Ce...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biomaterials
Egile Nagusiak: Hoang, Bryan, Ernsting, Mark J., Roy, Aniruddha, Murakami, Mami, Undzys, Elijus, Li, Shyh-Dar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442760/
https://ncbi.nlm.nih.gov/pubmed/25956852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.04.032
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