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Factors Controlling the Pharmacokinetics, Biodistribution and Intratumoral Penetration of Nanoparticles
Nanoparticle drug delivery to the tumor is impacted by multiple factors: nanoparticles must evade clearance by renal filtration and the reticuloendothelial system, extravasate through the enlarged endothelial gaps in tumors, penetrate through dense stroma in the tumor microenvironment to reach the t...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3891171/ https://ncbi.nlm.nih.gov/pubmed/24075927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.09.013 |
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