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Substrate Recognition and Modification by the Nosiheptide Resistance Methyltransferase

BACKGROUND: The proliferation of antibiotic resistant pathogens is an increasing threat to the general public. Resistance may be conferred by a number of mechanisms including covalent or mutational modification of the antibiotic binding site, covalent modification of the drug, or the over-expression...

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Publicat a:PLoS One
Autors principals: Yin, Sitao, Jiang, Hengyi, Chen, Dongrong, Murchie, Alastair I. H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409310/
https://ncbi.nlm.nih.gov/pubmed/25910005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122972
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