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Knockdown of SALL4 Protein Enhances All-trans Retinoic Acid-induced Cellular Differentiation in Acute Myeloid Leukemia Cells

All-trans retinoic acid (ATRA) is a differentiation agent that revolutionized the treatment of acute promyelocytic leukemia. However, it has not been useful for other types of acute myeloid leukemia (AML). Here we explored the effect of SALL4, a stem cell factor, on ATRA-induced AML differentiation...

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Publicado en:J Biol Chem
Autores principales: Liu, Li, Liu, Liang, Leung, Lai-Han, Cooney, Austin J., Chen, Changyi, Rosengart, Todd K., Ma, Yupo, Yang, Jianchang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409227/
https://ncbi.nlm.nih.gov/pubmed/25737450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.634790
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