Efficacy of All-Trans-Retinoic Acid in High-Risk Acute Myeloid Leukemia with Overexpression of EVI1

INTRODUCTION: EVI1 (MECOM)-positive acute myeloid leukemia (AML) cells have shown in vitro sensitivity to all-trans-retinoic acid (ATRA) by inducing differentiation, cell death, and decreased leukemic engraftment. METHODS: In this pilot study, we investigated the response to ATRA in 13 high-risk AML...

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Publicat a:Oncol Ther
Autors principals: Paubelle, Etienne, Plesa, Adriana, Hayette, Sandrine, Elhamri, Mohamed, Zylbersztejn, Florence, Hermine, Olivier, Salles, Gilles, Thomas, Xavier
Format: Artigo
Idioma:Inglês
Publicat: Springer Healthcare 2019
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Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359977/
https://ncbi.nlm.nih.gov/pubmed/32699982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40487-019-0095-9
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