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Knockdown of SALL4 Protein Enhances All-trans Retinoic Acid-induced Cellular Differentiation in Acute Myeloid Leukemia Cells

All-trans retinoic acid (ATRA) is a differentiation agent that revolutionized the treatment of acute promyelocytic leukemia. However, it has not been useful for other types of acute myeloid leukemia (AML). Here we explored the effect of SALL4, a stem cell factor, on ATRA-induced AML differentiation...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Liu, Li, Liu, Liang, Leung, Lai-Han, Cooney, Austin J., Chen, Changyi, Rosengart, Todd K., Ma, Yupo, Yang, Jianchang
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409227/
https://ncbi.nlm.nih.gov/pubmed/25737450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.634790
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