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Guanidinium-Rich, Glycerol-Derived Oligocarbonates: A New Class of Cell-Penetrating Molecular Transporters That Complex, Deliver, and Release siRNA

[Image: see text] A highly versatile and step-economical route to a new class of guanidinium-rich molecular transporters and evaluation of their ability to complex, deliver, and release siRNA are described. These new drug/probe delivery systems are prepared in only two steps, irrespective of length...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Wender, Paul A., Huttner, Melanie A., Staveness, Daryl, Vargas, Jessica R., Xu, Adele F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409141/
https://ncbi.nlm.nih.gov/pubmed/25588140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500581r
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