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Development of Guanidinium-rich Protein Mimics for Efficient siRNA Delivery into Human T Cells

RNA interference is gaining attention as a means to explore new molecular pathways and for its potential as a therapeutic; however, its application in immortal and primary T cells is limited due to challenges with efficient delivery in these cells types. Herein, we report the development of guanidin...

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Detalhes bibliográficos
Publicado no:Biomacromolecules
Main Authors: deRonde, Brittany M., Torres, Joe A., Minter, Lisa M., Tew, Gregory N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964960/
https://ncbi.nlm.nih.gov/pubmed/26324222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.5b00795
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