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A novel mechanism of LIN-28 regulation of let-7 microRNA expression revealed by in vivo HITS-CLIP in C. elegans

The evolutionarily conserved gene lin-28 encodes an RNA-binding protein and is an important regulator of the proper temporal succession of several developmental events in both invertebrates and vertebrates. At the cellular level, LIN-28 promotes stemness and proliferation, and inhibits differentiati...

詳細記述

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書誌詳細
出版年:RNA
主要な著者: Stefani, Giovanni, Chen, Xiaowei, Zhao, Hongyu, Slack, Frank J.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408804/
https://ncbi.nlm.nih.gov/pubmed/25805859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.045542.114
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