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Spliceosome assembly in the absence of stable U4/U6 RNA pairing
The cycle of spliceosome assembly, intron excision, and spliceosome disassembly involves large-scale structural rearrangements of U6 snRNA that are functionally important. U6 enters the splicing pathway bound to the Prp24 protein, which chaperones annealing of U6 to U4 RNA to form a U4/U6 di-snRNP....
Guardat en:
| Publicat a: | RNA |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408799/ https://ncbi.nlm.nih.gov/pubmed/25762536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.048421.114 |
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