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Photoreceptors in whirler mice show defective transducin translocation and are susceptible to short-term light/dark changes-induced degeneration

Usher syndrome combines congenital hearing loss and retinitis pigmentosa (RP). Mutations in the whirlin gene (DFNB31/WHRN) cause a subtype of Usher syndrome (USH2D). Whirler mice have a defective whirlin gene. They have inner ear defects but usually do not develop retinal degeneration. Here we repor...

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Publicat a:Exp Eye Res
Autors principals: Tian, Mei, Wang, Weimin, Delimont, Duane, Cheung, Linda, Zallocchi, Marisa, Cosgrove, Dominic, Peng, You-Wei
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408763/
https://ncbi.nlm.nih.gov/pubmed/24211856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2013.10.021
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