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Moderate Light-Induced Degeneration of Rod Photoreceptors with Delayed Transducin Translocation in shaker1 Mice

PURPOSE. Usher syndrome is characterized by congenital deafness associated with retinitis pigmentosa (RP). Mutations in the myosin VIIa gene (MYO7A) cause a common and severe subtype of Usher syndrome (USH1B). Shaker1 mice have mutant MYO7A. They are deaf and have vestibular dysfunction but do not d...

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Detalhes bibliográficos
Main Authors: Peng, You-Wei, Zallocchi, Marisa, Wang, Wei-Min, Delimont, Duane, Cosgrove, Dominic
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176018/
https://ncbi.nlm.nih.gov/pubmed/21447681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6557
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