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Absence of integrin α1β1 results in transducin translocation defects, matrix accumulation in the basal lamina of the RPE, and photoreceptor cell degeneration in mice

PURPOSE: The role of integrin/cell matrix interactions between the RPE and the basement membrane in retinal maintenance and function is not well characterized.In this study the functional importance of α1β1 integrin for RPE cell homeostasis and retinal health was assessed by comparing α1 integrin kn...

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Main Authors: Peng, You-Wei, Zallocchi, Marisa, Meehan, Daniel T., Delimont, Duane, Chang, Bo, Hawes, Norman, Wang, Weimin, Cosgrove, Dominic
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2625300/
https://ncbi.nlm.nih.gov/pubmed/18614805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2011
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