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Absence of integrin α1β1 results in transducin translocation defects, matrix accumulation in the basal lamina of the RPE, and photoreceptor cell degeneration in mice
PURPOSE: The role of integrin/cell matrix interactions between the RPE and the basement membrane in retinal maintenance and function is not well characterized.In this study the functional importance of α1β1 integrin for RPE cell homeostasis and retinal health was assessed by comparing α1 integrin kn...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2625300/ https://ncbi.nlm.nih.gov/pubmed/18614805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2011 |
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