T cell receptor binding affinity governs the functional profile of cancer-specific CD8(+) T cells

Lignende værker

• Human leucocyte antigen class I‐redirected anti‐tumour CD4(+) T cells require a higher T cell receptor binding affinity for optimal activity than CD8(+) T cells
  af: Tan, M. P., et al.
  Udgivet: (2016)
• Improved affinity AFP-specific T cell receptor for hepatocellular carcinoma
  af: Gerry, Andrew B, et al.
  Udgivet: (2013)
• Clonotypically similar hybrid αβ T cell receptors can exhibit markedly different surface expression, antigen specificity and cross‐reactivity
  af: Motozono, C., et al.
  Udgivet: (2015)
• CD8(+) T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold
  af: Dockree, Tamsin, et al.
  Udgivet: (2017)
• CD3ζ-based chimeric antigen receptors mediate T cell activation via cis- and trans-signalling mechanisms: implications for optimization of receptor structure for adoptive cell therapy
  af: Bridgeman, J S, et al.
  Udgivet: (2014)