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Clonotypically similar hybrid αβ T cell receptors can exhibit markedly different surface expression, antigen specificity and cross‐reactivity

Emerging data indicate that particular major histocompatibility complex (MHC)‐bound antigenic peptides can be recognized by identical or near‐identical αβ T cell receptors (TCRs) in different individuals. To establish the functional relevance of this phenomenon, we artificially paired α and β chains...

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Bibliografische gegevens
Gepubliceerd in:Clin Exp Immunol
Hoofdauteurs: Motozono, C., Bridgeman, J. S., Price, D. A., Sewell, A. K., Ueno, T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449784/
https://ncbi.nlm.nih.gov/pubmed/25721491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12610
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