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Oxidative stress conditions increase the frequency of de novo formation of the yeast [PSI (+)] prion

Prions are self‐perpetuating amyloid protein aggregates which underlie various neurodegenerative diseases in mammals and heritable traits in yeast. The molecular basis of how yeast and mammalian prions form spontaneously into infectious amyloid‐like structures is poorly understood. We have explored...

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Detalhes bibliográficos
Publicado no:Mol Microbiol
Main Authors: Doronina, Victoria A., Staniforth, Gemma L., Speldewinde, Shaun H., Tuite, Mick F., Grant, Chris M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407919/
https://ncbi.nlm.nih.gov/pubmed/25601439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12930
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