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Disrupting the cortical actin cytoskeleton points to two distinct mechanisms of yeast [PSI(+)] prion formation
Mammalian and fungal prions arise de novo; however, the mechanism is poorly understood in molecular terms. One strong possibility is that oxidative damage to the non-prion form of a protein may be an important trigger influencing the formation of its heritable prion conformation. We have examined th...
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| Publié dans: | PLoS Genet |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5393896/ https://ncbi.nlm.nih.gov/pubmed/28369054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006708 |
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