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Ribosome-associated peroxiredoxins suppress oxidative stress–induced de novo formation of the [PSI(+)] prion in yeast
Peroxiredoxins (Prxs) are ubiquitous antioxidants that protect cells against oxidative stress. We show that the yeast Tsa1/Tsa2 Prxs colocalize to ribosomes and function to protect the Sup35 translation termination factor against oxidative stress–induced formation of its heritable [PSI(+)] prion con...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851942/ https://ncbi.nlm.nih.gov/pubmed/20308573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000347107 |
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