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Distinct effects of ubiquitin overexpression on NMJ structure and motor performance in mice expressing catalytically inactive USP14
Ubiquitin-specific protease 14 (USP14) is a major deubiquitinating enzyme and a key determinant of neuromuscular junction (NMJ) structure and function. We have previously reported dramatic ubiquitin depletion in the nervous systems of the USP14-deficient ataxia (ax(J)) mice and demonstrated that tra...
Gespeichert in:
| Veröffentlicht in: | Front Mol Neurosci |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4407586/ https://ncbi.nlm.nih.gov/pubmed/25954152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2015.00011 |
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