A catalytic independent function of the deubiquitinating enzyme USP14 regulates hippocampal synaptic short-term plasticity and vesicle number

AbstractThe ubiquitin proteasome system is required for the rapid and precise control of protein abundance that is essential for synaptic function. USP14 is a proteasome-bound deubiquitinating enzyme that recycles ubiquitin and regulates synaptic short-term synaptic plasticity. We previously reporte...

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Bibliographische Detailangaben
Hauptverfasser: Walters, Brandon J, Hallengren, Jada J, Theile, Christopher S, Ploegh, Hidde L, Wilson, Scott M, Dobrunz, Lynn E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2014
Schlagworte:
Neuroscience: Cellular/Molecular
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934702/
https://ncbi.nlm.nih.gov/pubmed/24218545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.266015
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