Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson’s disease models

Nicotinamide adenine dinucleotide phosphate oxidase, a key superoxide-producing enzyme, plays a critical role in microglia-mediated chronic neuroinflammation and subsequent progressive dopaminergic neurodegeneration in Parkinson’s disease. Although nicotinamide adenine dinucleotide phosphate oxidase...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Wang, Qingshan, Qian, Li, Chen, Shih-Heng, Chu, Chun-Hsien, Wilson, Belinda, Oyarzabal, Esteban, Ali, Syed, Robinson, Bonnie, Rao, Deepa, Hong, Jau-Shyong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407187/
https://ncbi.nlm.nih.gov/pubmed/25716193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv034
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