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XIAP and cIAP1 amplifications induce Beclin 1-dependent autophagy through NFκB activation
Perturbations in autophagy and apoptosis are associated with cancer development. XIAP and cIAP1 are two members of the inhibitors of apoptosis protein family whose expression is elevated in different cancers. Here we report that XIAP and cIAP1 induce autophagy by upregulating the transcription of Be...
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4406300/ https://ncbi.nlm.nih.gov/pubmed/25669656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv052 |
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