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STIM1L traps and gates Orai1 channels without remodeling the cortical ER
STIM proteins populate and expand cortical endoplasmic reticulum (ER) sheets to mediate store-operated Ca(2+) entry (SOCE) by trapping and gating Orai channels in ER-plasma membrane clusters. A longer splice variant, STIM1L, forms permanent ER-plasma membrane clusters and mediates rapid Ca(2+) influ...
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| 發表在: | J Cell Sci |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Company of Biologists
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4406124/ https://ncbi.nlm.nih.gov/pubmed/25736291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.164228 |
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