Resveratrol protects against doxorubicin-induced cardiotoxicity in aged hearts through the SIRT1-USP7 axis

A compromised cardiac function is often seen in elderly cancer patients receiving doxorubicin therapy. The present study tested the hypothesis that acute intervention with resveratrol, a natural anti-oxidant found in grapes and red wine, reduces the cardiotoxicity of doxorubicin through restoration...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Physiol
Egile Nagusiak: Sin, Thomas K, Tam, Bjorn T, Yung, Benjamin Y, Yip, Shea P, Chan, Lawrence W, Wong, Cesar S, Ying, Michael, Rudd, John A, Siu, Parco M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BlackWell Publishing Ltd 2015
Gaiak:
Cardiovascular
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405749/
https://ncbi.nlm.nih.gov/pubmed/25665036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.270101
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