Doxorubicin Induces Inflammatory Modulation and Metabolic Dysregulation in Diabetic Skeletal Muscle

Anti-cancer agent doxorubicin (DOX) has been demonstrated to worsen insulin signaling, engender muscle atrophy, trigger pro-inflammation, and induce a shift to anaerobic glycolytic metabolism in skeletal muscle. The myotoxicity of DOX in diabetic skeletal muscle remains largely unclear. This study e...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Supriya, Rashmi, Tam, Bjorn T., Pei, Xiao M., Lai, Christopher W., Chan, Lawrence W., Yung, Benjamin Y., Siu, Parco M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961708/
https://ncbi.nlm.nih.gov/pubmed/27512375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00323
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