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Protective Effect of Unacylated Ghrelin on Compression-Induced Skeletal Muscle Injury Mediated by SIRT1-Signaling

Unacylated ghrelin, the predominant form of circulating ghrelin, protects myotubes from cell death, which is a known attribute of pressure ulcers. In this study, we investigated whether unacylated ghrelin protects skeletal muscle from pressure-induced deep tissue injury by abolishing necroptosis and...

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Veröffentlicht in:Front Physiol
Hauptverfasser: Ugwu, Felix N., Yu, Angus P., Sin, Thomas K., Tam, Bjorn T., Lai, Christopher W., Wong, S. C., Siu, Parco M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705540/
https://ncbi.nlm.nih.gov/pubmed/29225581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00962
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