Alternative Splicing of SMPD1 in Human Sepsis

Acid sphingomyelinase (ASM or sphingomyelin phosphodiesterase, SMPD) activity engages a critical role for regulation of immune response and development of organ failure in critically ill patients. Beside genetic variation in the human gene encoding ASM (SMPD1), alternative splicing of the mRNA is in...

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Vydáno v:PLoS One
Hlavní autoři: Kramer, Marcel, Quickert, Stefanie, Sponholz, Christoph, Menzel, Uwe, Huse, Klaus, Platzer, Matthias, Bauer, Michael, Claus, Ralf A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405572/
https://ncbi.nlm.nih.gov/pubmed/25898364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124503
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