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Alternative Splicing of SMPD1 in Human Sepsis

Acid sphingomyelinase (ASM or sphingomyelin phosphodiesterase, SMPD) activity engages a critical role for regulation of immune response and development of organ failure in critically ill patients. Beside genetic variation in the human gene encoding ASM (SMPD1), alternative splicing of the mRNA is in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kramer, Marcel, Quickert, Stefanie, Sponholz, Christoph, Menzel, Uwe, Huse, Klaus, Platzer, Matthias, Bauer, Michael, Claus, Ralf A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405572/
https://ncbi.nlm.nih.gov/pubmed/25898364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124503
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