Polymorphisms of cystathionine beta-synthase gene are associated with susceptibility to sepsis

Sepsis is the systemic inflammatory host response to infection. Cystathionine beta-synthase (CBS)-dependent homocysteine (Hcy) pathway was demonstrated to affect disease severity and mortality in patients with severe sepsis/septic shock. Independent studies identified a single-nucleotide polymorphis...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Eur J Hum Genet
Prif Awduron: Sponholz, Christoph, Kramer, Marcel, Schöneweck, Franziska, Menzel, Uwe, Inanloo Rahatloo, Kolsoum, Giamarellos-Bourboulis, Evangelos J, Papavassileiou, Vassileios, Lymberopoulou, Korina, Pavlaki, Maria, Koutelidakis, Ioannis, Perdios, Ioannis, Scherag, André, Bauer, Michael, Platzer, Matthias, Huse, Klaus
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070885/
https://ncbi.nlm.nih.gov/pubmed/26508567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.231
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