लोड हो रहा है...
The molecular basis of antifolate resistance in Plasmodium falciparum: looking beyond point mutations
Drugs that target the folate synthesis pathway have a long history of effectiveness against a variety of pathogens. As antimalarials, the antifolates were safe and well tolerated, but resistance emerged quickly and has persisted even with decreased drug pressure. The primary determinants of resistan...
में बचाया:
में प्रकाशित: | Ann N Y Acad Sci |
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मुख्य लेखकों: | , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2015
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4405445/ https://ncbi.nlm.nih.gov/pubmed/25694157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12662 |
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