Escalating Plasmodium falciparum antifolate drug resistance mutations in Macha, rural Zambia

BACKGROUND: In Zambia the first-line treatment for uncomplicated malaria is artemisinin combination therapy (ACT), with artemether-lumefantrine currently being used. However, the antifolate regimen, sulphadoxine-pyrimethamine (SP), remains the treatment of choice in children weighing less than 5 kg...

Full description

Saved in:
Bibliographic Details
Main Authors: Mkulama, Mtawa AP, Chishimba, Sandra, Sikalima, Jay, Rouse, Petrica, Thuma, Philip E, Mharakurwa, Sungano
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2412897/
https://ncbi.nlm.nih.gov/pubmed/18495008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-7-87
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items