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Malaria antifolate resistance with contrasting Plasmodium falciparum dihydrofolate reductase (DHFR) polymorphisms in humans and Anopheles mosquitoes

Surveillance for drug-resistant parasites in human blood is a major effort in malaria control. Here we report contrasting antifolate resistance polymorphisms in Plasmodium falciparum when parasites in human blood were compared with parasites in Anopheles vector mosquitoes from sleeping huts in rural...

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Detalhes bibliográficos
Main Authors: Mharakurwa, Sungano, Kumwenda, Taida, Mkulama, Mtawa A. P., Musapa, Mulenga, Chishimba, Sandra, Shiff, Clive J., Sullivan, David J., Thuma, Philip E., Liu, Kun, Agre, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219121/
https://ncbi.nlm.nih.gov/pubmed/22065788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116162108
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