Malaria antifolate resistance with contrasting Plasmodium falciparum dihydrofolate reductase (DHFR) polymorphisms in humans and Anopheles mosquitoes

Surveillance for drug-resistant parasites in human blood is a major effort in malaria control. Here we report contrasting antifolate resistance polymorphisms in Plasmodium falciparum when parasites in human blood were compared with parasites in Anopheles vector mosquitoes from sleeping huts in rural...

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Main Authors: Mharakurwa, Sungano, Kumwenda, Taida, Mkulama, Mtawa A. P., Musapa, Mulenga, Chishimba, Sandra, Shiff, Clive J., Sullivan, David J., Thuma, Philip E., Liu, Kun, Agre, Peter
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219121/
https://ncbi.nlm.nih.gov/pubmed/22065788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116162108
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