Escalating Plasmodium falciparum antifolate drug resistance mutations in Macha, rural Zambia

BACKGROUND: In Zambia the first-line treatment for uncomplicated malaria is artemisinin combination therapy (ACT), with artemether-lumefantrine currently being used. However, the antifolate regimen, sulphadoxine-pyrimethamine (SP), remains the treatment of choice in children weighing less than 5 kg...

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Detalhes bibliográficos
Main Authors: Mkulama, Mtawa AP, Chishimba, Sandra, Sikalima, Jay, Rouse, Petrica, Thuma, Philip E, Mharakurwa, Sungano
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2412897/
https://ncbi.nlm.nih.gov/pubmed/18495008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-7-87
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