A carregar...
Direct evidence for the adaptive role of copy number variation on antifolate susceptibility in Plasmodium falciparum
Resistance to antimalarials targeting the folate pathway is widespread. GTP-cyclohydrolase (gch1), the first enzyme in this pathway, exhibits extensive copy number variation (CNV) in parasite isolates from areas with a history of longstanding antifolate use. Increased CN of gch1 is associated with a...
Na minha lista:
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3654098/ https://ncbi.nlm.nih.gov/pubmed/23347134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12162 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|