Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors.

The cAMP response element binding protein (CREB) has been implicated as a key regulator in the transcriptional control of many genes. To assess the functional importance of CREB in vivo and its role in development, we used gene targeting to generate mice with a disruption of the CREB gene. Homozygou...

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Hlavní autoři: Hummler, E, Cole, T J, Blendy, J A, Ganss, R, Aguzzi, A, Schmid, W, Beermann, F, Schütz, G
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC44053/
https://ncbi.nlm.nih.gov/pubmed/8202542
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