Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors.

The cAMP response element binding protein (CREB) has been implicated as a key regulator in the transcriptional control of many genes. To assess the functional importance of CREB in vivo and its role in development, we used gene targeting to generate mice with a disruption of the CREB gene. Homozygou...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hummler, E, Cole, T J, Blendy, J A, Ganss, R, Aguzzi, A, Schmid, W, Beermann, F, Schütz, G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44053/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8202542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.12.5647
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