Mouse Model for Human Arginase Deficiency

Deficiency of liver arginase (AI) causes hyperargininemia (OMIM 207800), a disorder characterized by progressive mental impairment, growth retardation, and spasticity and punctuated by sometimes fatal episodes of hyperammonemia. We constructed a knockout mouse strain carrying a nonfunctional AI gene...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Iyer, Ramaswamy K., Yoo, Paul K., Kern, Rita M., Rozengurt, Nora, Tsoa, Rosemarie, O'Brien, William E., Yu, Hong, Grody, Wayne W., Cederbaum, Stephen D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2002
Ämnen:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC133904/
https://ncbi.nlm.nih.gov/pubmed/12052859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4491-4498.2002
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk