Mouse Model for Human Arginase Deficiency

Deficiency of liver arginase (AI) causes hyperargininemia (OMIM 207800), a disorder characterized by progressive mental impairment, growth retardation, and spasticity and punctuated by sometimes fatal episodes of hyperammonemia. We constructed a knockout mouse strain carrying a nonfunctional AI gene...

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Bibliographic Details
Published in:	Mol Cell Biol
Main Authors:	Iyer, Ramaswamy K., Yoo, Paul K., Kern, Rita M., Rozengurt, Nora, Tsoa, Rosemarie, O'Brien, William E., Yu, Hong, Grody, Wayne W., Cederbaum, Stephen D.
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 2002
Subjects:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12052859/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.13.4491-4498.2002
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Mouse Model for Human Arginase Deficiency

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