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Identification of Destabilizing and Stabilizing Mutations of Ste2p, a G Protein Coupled Receptor in Saccharomyces cerevisiae
The isolation of mutations affecting the stabilities of transmembrane proteins is useful for enhancing the suitability of proteins for structural characterization and for identification of determinants of membrane protein stability. We have pursued a strategy for identification of stabilized variant...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4405178/ https://ncbi.nlm.nih.gov/pubmed/25647246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501314t |
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