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Single-cell genotyping demonstrates complex clonal diversity in acute myeloid leukemia
Clonal evolution in cancer – the selection for and emergence of increasingly malignant clones during progression and therapy, resulting in cancer metastasis and relapse – has been highlighted as an important phenomenon in the biology of leukemia and other cancers. Tracking mutant alleles to determin...
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| Pubblicato in: | Sci Transl Med |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4405099/ https://ncbi.nlm.nih.gov/pubmed/25834112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa0763 |
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