Self-digitization chip for single-cell genotyping of cancer-related mutations

Cancer is a heterogeneous disease, and patient-level genetic assessments can guide therapy choice and impact prognosis. However, little is known about the impact of genetic variability within a tumor, intratumoral heterogeneity (ITH), on disease progression or outcome. Current approaches using bulk...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Thompson, Alison M., Smith, Jordan L., Monroe, Luke D., Kreutz, Jason E., Schneider, Thomas, Fujimoto, Bryant S., Chiu, Daniel T., Radich, Jerald P., Paguirigan, Amy L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931502/
https://ncbi.nlm.nih.gov/pubmed/29718986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196801
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