Self-Digitization Dielectrophoretic (SD-DEP) Chip for High Efficiency Single-Cell Capture, On-Demand Compartmentalization, and Downstream Nucleic-Acid Analysis

This communication describes the design and fabrication of SD-DEP chip with simple components for single-cell manipulation and downstream nucleic acid analysis. The device employed the traditional DEP and insulator DEP to create the local electric field that is tailored to approximately the size of...

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Bibliographic Details
Published in:Angew Chem Int Ed Engl
Main Authors: Qin, Y, Wu, L, Schneider, T, Yen, GS, Wang, J, Xu, S, Li, M, Paguirigan, AL, Smith, JL, Radich, JP, Anand, RK, Chiu, DT
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457344/
https://ncbi.nlm.nih.gov/pubmed/30003660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201807314
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